Endocrine Abstracts

Recently we described clinical case of 38-year-old fertile woman with sudden onset of a multiple clinical symptoms: weight gain, secondary amenorrhea, hirsutism and seizures. Adrenal tumour co-secreted high amounts of DHEA sulfate, testosterone (T) and aldosterone (A) (Matulevicius et al. 2014). The symptoms of the disease disappeared after laparoscopic removal of adrenal tumour, which proved to be an adrenocortical oncocytoma. A hypersecretion of A remained after res...

The 1772 patients were referred for the dehydroepiandrosterone sulphate (DHEA-S) concentration assessment in Lithuania during 2014. We investigated 309 clinical history cases of which 162 presented with normal DHEA-S concentration and 147 with elevated one.One hundred twenty-three women with increased DHEA-S were examined. The following symptoms were found: hirsutism −39%, menstruation disorders −23%, weight gain −8%, and the rest &#872...